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Article

Genetic variants of the Renin Angiotensin system: effects on atherosclerosis in experimental models and humans.

Current atherosclerosis reports - 1 May 2010

Daugherty Alan, Poduri Aruna, Chen Xiaofeng, Lu Hong, Cassis Lisa A

Abstract excerpt

The renin angiotensin system (RAS) has profound effects on atherosclerosis development in animal models, which is partially complimented by evidence in the human disease. Although angiotensin II was considered to be the principal effector of the RAS, a broader array of bioactive angiotensin peptides have been identified that have increased the scope of enzymes and receptors in the RAS. Genetic interruption of the...

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Identifiers

PMID: 20425255
DOI: 10.1007/s11883-010-0109-4
PMCID: PMC2857789

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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