Article
Aspects of gene polymorphisms in cardiovascular disease: the renin-angiotensin system.
European journal of clinical investigation - 1 Jun 2001
Carluccio M, Soccio M, De Caterina R
Abstract excerpt
The renin-angiotensin system (RAS) plays a central role in cardiovascular homeostasis. Angiotensin is the key peptide of the RAS, and exerts its influence on the heart and blood vessels both through its haemodynamic effects (via its influence on after-load and pre-load and determining coronary vasoconstriction) and through its direct cellular effects (via its actions on cell proliferation). Numerous studies in...
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