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Article

A genetic risk score composed of rheumatoid arthritis risk alleles, HLA-DRB1 haplotypes, and response to TNFi therapy - results from a Swedish cohort study.

Arthritis research & therapy - 3 Dec 2016

Jiang Xia, Askling Johan, Saevarsdottir Saedis, Padyukov Leonid, Alfredsson Lars, Viatte Sebastien, Frisell Thomas

Abstract excerpt

BACKGROUND: To prevent debilitating and irreversible joint damage, rheumatoid arthritis (RA) is often treated with tumor necrosis factor inhibitor (TNFi), but many patients do not respond to this costly therapy. Few predictors for response are known, and it has been proposed that genetic factors which influence the development of RA may also influence disease severity and response to therapy. Several previous...

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Identifiers

PMID: 27912794
DOI: 10.1186/s13075-016-1174-z
PMCID: PMC5135751

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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