Article
High-content, image-based screening for drug targets in yeast.
PloS one - 14 Apr 2010
Ohnuki Shinsuke, Oka Satomi, Nogami Satoru, Ohya Yoshikazu
Abstract excerpt
BACKGROUND: Drug discovery and development are predicated on elucidation of the potential mechanisms of action and cellular targets of candidate chemical compounds. Recent advances in high-content imaging techniques allow simultaneous analysis of a range of cellular events. In this study, we propose a novel strategy to identify drug targets by combining genetic screening and high-content imaging in yeast....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.