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Article

Canonical Notch signaling is not required for the growth of Hedgehog pathway-induced medulloblastoma.

Oncogene - 17 Jun 2010

Julian E, Dave R K, Robson J P, Hallahan A R, Wainwright B J

Abstract excerpt

Current treatment for medulloblastoma is successful in more than half of all cases but results in substantial disability in survivors. Accordingly, there is considerable interest in drugs that may target specific signaling pathways activated in the tumors, with inhibitors of both the Hedgehog and Notch pathways currently proposed as possible therapeutics. Here, we tested the hypothesis that Notch pathway...

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Identifiers

PMID: 20418906
DOI: 10.1038/onc.2010.101

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GFAP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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