Article
Characterization of a Norovirus-specific monoclonal antibody that exhibits wide spectrum binding activities.
Journal of medical virology - 1 Apr 2018
Zheng Lijun, Wang Wenhui, Liu Jinjin, Chen Xuhui, Li Sanjing, Wang Qiaoli, Huo Yuqi, Qin Chuan, Shen Shuo, Wang Mingchen
Abstract excerpt
Noroviruses (NoVs) are increasingly recognized as the leading cause of acute non-bacterial gastroenteritis worldwide. To screen for NoV-specific monoclonal antibodies (mAbs) with wide spectrum binding activities that could be used for the development of NoV-related detection reagents, we immunized mice with a combination of virus like particles (VLPs) derived from eight different genotypes (two from genogroup I...
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