BioMog: a computational framework for the de novo generation or modification of essential biomass components.

Abstract excerpt

The success of genome-scale metabolic modeling is contingent on a model's ability to accurately predict growth and metabolic behaviors. To date, little focus has been directed towards developing systematic methods of proposing, modifying and interrogating an organism's biomass requirements that are used in constraint-based models. To address this gap, the biomass modification and generation (BioMog) framework was...

Topics

• Biomass
• Escherichia coli
• Genomics
• Models, Biological
• Phenotype
• Shewanella