Article
Hepatitis B virus-related hepatocarcinogenesis: molecular oncogenic potential of clear or occult infections.
European journal of cancer (Oxford, England : 1990) - 1 Aug 2010
De Mitri Maria Stella, Cassini Romina, Bernardi Mauro
Abstract excerpt
Chronic viral infection is the most important oncogenetic factor, and hepatitis B virus (HBV) plays an important role in the development of hepatocellular carcinoma (HCC). HBV-related carcinogenesis is a multi-step process, encompassing the combination of different, not mutually exclusive effects...
Topics
- Carcinoma, Hepatocellular
- DNA, Viral
- Genome, Viral
- Genotype
- Hepatitis B virus
- Hepatitis B, Chronic
- Humans
- Liver Cirrhosis
- Mutation
- Neoplasms
- Oncogenes
- Viral Load
- Virus Replication
