Article
Hepatitis B virus-related hepatocarcinogenesis: molecular oncogenic potential of clear or occult infections.
European journal of cancer (Oxford, England : 1990) - 1 Aug 2010
De Mitri Maria Stella, Cassini Romina, Bernardi Mauro
Abstract excerpt
Chronic viral infection is the most important oncogenetic factor, and hepatitis B virus (HBV) plays an important role in the development of hepatocellular carcinoma (HCC). HBV-related carcinogenesis is a multi-step process, encompassing the combination of different, not mutually exclusive effects such as the induction of chronic liver inflammation and regeneration, its integration into the hepatocyte genome and...
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