Article
The direct and indirect roles of HBV in liver cancer: prospective markers for HCC screening and potential therapeutic targets.
The Journal of pathology - 1 Jan 2015
Ringelhan Marc, O'Connor Tracy, Protzer Ulrike, Heikenwalder Mathias
Abstract excerpt
Chronic hepatitis B virus (HBV) infection remains the number one risk factor for hepatocellular carcinoma (HCC), accounting for more than 600 000 deaths/year. Despite highly effective antiviral treatment options, chronic hepatitis B (CHB), subsequent end-stage liver disease and HCC development remain a major challenge worldwide. In CHB, liver damage is mainly caused by the influx of immune cells and destruction...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.