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Article

Synergistic impact of mutations in Hepatitis B Virus genome contribute to its occult phenotype in chronic Hepatitis C Virus carriers.

Scientific reports - 29 Aug 2017

Mondal Rajiv Kumar, Khatun Mousumi, Banerjee Priyanka, Ghosh Alip, Sarkar Sumanta, Santra Amal, Das Kausik, Chowdhury Abhijit, Banerjee Soma, Datta Simanti

Abstract excerpt

We characterized occult HBV (OHBV) from hepatitis B surface antigen (HBsAg)-negative chronic HCV carriers of Eastern India to explore the impact of genomic variability of HBV in causing undetectability of HBsAg and low viremia that define the occult phenomenon. Screening of sera samples revealed the presence of OHBV in 17.8% of HCV-infected patients. Determination of full-length OHBV sequences and comparison with...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 28852072
DOI: 10.1038/s41598-017-09965-w
PMCID: PMC5574988

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