Mechanisms of HBV-related hepatocarcinogenesis

doi:10.1016/j.jhep.2009.10.033

Article

Mechanisms of HBV-related hepatocarcinogenesis

8 Jan 2010

Abstract excerpt

The hepatitis B virus (HBV) is a small enveloped DNA virus, which primarily infects hepatocytes and causes acute and persistent liver disease. Epidemiological studies have provided overwhelming evidence for a causal role of chronic HBV infection in the development of hepatocellular carcinoma, but the molecular mechanisms underlying virally-induced tumourigenesis remain largely debated. In the absence of a...

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