Article
Apolipoprotein E ε4 allele impairs cortical activity in healthy aging and Alzheimer's disease.
Behavioural brain research - 26 Feb 2022
Pedroso Renata Valle, Fraga Francisco José, Nascimento Carla Manuela Crispim, Pott-Junior Henrique, Cominetti Márcia Regina
Abstract excerpt
AIM: To investigate the influence of apolipoprotein E (APOE) genotype on cortical activity, using the event-related potential P300 in healthy older adults and individuals with Alzheimer's disease (AD). METHODS: A cohort of 37 healthy older adults and 48 with AD participated in this study and completed an auditory oddball task using electroencephalographic equipment with 21 channels (10-20 system). APOE genotyping...
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