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Article

High resolution analysis of genomic aberrations by metaphase and array comparative genomic hybridization identifies candidate tumour genes in lung cancer cell lines.

Cancer letters - 8 Jan 2007

Zhu Hong, Lam David Chi Leung, Han Kam Chu, Tin Vicky Pui Chi, Suen Wai Sing, Wang Elaine, Lam Wah Kit, Cai Wei Wen, Chung Lap Ping, Wong Maria Pik

Abstract excerpt

Tumours develop from clonally expanded population of cells harbouring aberrations of oncogenes and tumour suppressor genes. In this study, metaphase and array comparative genomic hybridization showed good correlation of aberration profiles in lung adenocarcinoma cell lines from patients with different tobacco exposure. Recurrent DNA gains were found at chromosomes 1, 7, 8, 17, 20, and deletions at 1, 3, 8, 9, 10,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16517066
DOI: 10.1016/j.canlet.2006.01.020

Genes

KLF6
AGR2
TPD52
WFDC2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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