Article
miR-146b is highly expressed in adult papillary thyroid carcinomas with high risk features including extrathyroidal invasion and the BRAF(V600E) mutation.
Thyroid : official journal of the American Thyroid Association - 1 May 2010
Chou Chen-Kai, Chen Rong-Fu, Chou Fong-Fu, Chang Hsueh-Wen, Chen Yi-Ju, Lee Ya-Fang, Yang Kuender D, Cheng Jiin-Tsuey, Huang Chao-Cheng, Liu Rue-Tsuan
Abstract excerpt
BACKGROUND: Papillary thyroid carcinoma (PTC) are clinicopathogenetically heterogeneous. Micro-RNAs (miRNAs) are involved in the pathogenesis of diverse human cancers, including PTC. Information regarding associations between clinicopathological features of PTC with the expression of specific miRNAs, however, is sparse. In this study, we compared expression of deregulated miRNAs in PTCs to assess this was...
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