Article
MicroRNA signature distinguishes the degree of aggressiveness of papillary thyroid carcinoma.
Annals of surgical oncology - 1 Jul 2011
Yip Linwah, Kelly Lindsey, Shuai Yongli, Armstrong Michaele J, Nikiforov Yuri E, Carty Sally E, Nikiforova Marina N
Abstract excerpt
BACKGROUND: Papillary thyroid carcinoma (PTC) has relatively indolent behavior, although some tumors recur and disseminate to distant sites. The aggressive biological behavior of PTC is difficult to predict. MicroRNAs (miRNAs) are dysregulated in various tumors types, and some of them serve as markers of poor prognosis. In this study, we evaluated miRNA expression as a marker of more aggressive behavior in PTC....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.