Article
An eGFP-based genetic screen for defects in light-triggered subcelluar translocation of the Drosophila photoreceptor channel TRPL.
Fly - 1 Jan 2000
Meyer Nina E, Oberegelsbacher Claudia, Dürr Thomas D, Schäfer Andrea, Huber Armin
Abstract excerpt
Signaling at the plasma membrane is modulated by up- and downregulation of signaling proteins. A prominent example for this type of regulation is the Drosophila TRPL ion channel that changes its spatial distribution within the photoreceptor cell. In dark-raised flies TRPL is localized in the rhabdomeral photoreceptor membrane and it translocates to the cell body upon illumination. It has been shown that TRPL...
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