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Article

Rac1 recruits the adapter protein CMS/CD2AP to cell-cell contacts.

The Journal of biological chemistry - 25 Jun 2010

van Duijn Trynette J, Anthony Eloise C, Hensbergen Paul J, Deelder André M, Hordijk Peter L

Abstract excerpt

Rac1 is a member of the Rho family of small GTPases, which regulate cell adhesion and migration through their control of the actin cytoskeleton. Rho-GTPases are structurally very similar, with the exception of a hypervariable domain in the C terminus. Using peptide-based pulldown assays in combination with mass spectrometry, we previously showed that the hypervariable domain in Rac1 mediates specific...

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Identifiers

PMID: 20404345
DOI: 10.1074/jbc.M109.099481
PMCID: PMC2888426

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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