Article
JRAB/MICAL-L2 is a junctional Rab13-binding protein mediating the endocytic recycling of occludin.
Molecular biology of the cell - 1 May 2006
Terai Tomoya, Nishimura Noriyuki, Kanda Ikuno, Yasui Natsuo, Sasaki Takuya
Abstract excerpt
The dynamic turnover of tight junctions (TJs) is essential for epithelial-mesenchymal transitions and/or mesenchymal-epithelial transitions during epithelial morphogenesis. We previously demonstrated that Rab13 specifically mediates the endocytic recycling of occludin. Here, we identified MICAL-L2 (molecule interacting with CasL-like 2) as a novel Rab13-binding protein. Immunoprecipitation and immunofluorescence...
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