Article
Domain organization and function in GluK2 subtype kainate receptors.
Proceedings of the National Academy of Sciences of the United States of America - 4 May 2010
Das Utpal, Kumar Janesh, Mayer Mark L, Plested Andrew J R
Abstract excerpt
Glutamate receptor ion channels (iGluRs) are excitatory neurotransmitter receptors with a unique molecular architecture in which the extracellular domains assemble as a dimer of dimers. The structure of individual dimer assemblies has been established previously for both the isolated ligand-binding domain (LBD) and more recently for the larger amino terminal domain (ATD). How these dimers pack to form tetrameric...
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