Article
Host-interactive genes in Amerindian Helicobacter pylori diverge from their Old World homologs and mediate inflammatory responses.
Journal of bacteriology - 1 Jun 2010
Mane S P, Dominguez-Bello M G, Blaser M J, Sobral B W, Hontecillas R, Skoneczka J, Mohapatra S K, Crasta O R, Evans C, Modise T, Shallom S, Shukla M, Varon C, Mégraud F, Maldonado-Contreras A L, Williams K P, Bassaganya-Riera J
Abstract excerpt
Helicobacter pylori is the dominant member of the gastric microbiota and has been associated with an increased risk of gastric cancer and peptic ulcers in adults. H. pylori populations have migrated and diverged with human populations, and health effects vary. Here, we describe the whole genome of the cag-positive strain V225d, cultured from a Venezuelan Piaroa Amerindian subject. To gain insight into the...
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