Article
Polymorphisms in the ACE and ADRB2 genes and risks of aging-associated phenotypes: the case of myocardial infarction.
Rejuvenation research - 1 Feb 2010
Kulminski Alexander M, Culminskaya Irina V, Ukraintseva Svetlana V, Arbeev Konstantin G, Akushevich Igor, Land Kenneth C, Yashin Anatoli I
Abstract excerpt
Multiple functions of the beta2-adrenergic receptor (ADRB2) and angiotensin-converting enzyme (ACE) genes warrant studies of their associations with aging-related phenotypes. We focus on multimarker analyses and analyses of the effects of compound genotypes of two polymorphisms in the ADRB2 gene, rs1042713 and rs1042714, and 11 polymorphisms of the ACE gene, on the risk of such an aging-associated phenotype as...
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