Article
Beta(2)-adrenergic receptor gene polymorphism, age, and cardiovascular phenotypes.
Hypertension (Dallas, Tex. : 1979) - 1 Feb 2003
Castellano Maurizio, Rossi Federica, Giacchè Mara, Perani Cristiano, Rivadossi Francesca, Muiesan Maria Lorenza, Salvetti Massimo, Beschi Marina, Rizzoni Damiano, Agabiti-Rosei Enrico
Abstract excerpt
Previous studies suggest that variants of the beta(2)-adrenergic receptor (ADRB2) may differently affect functional responses to adrenergic stimulation, thereby possibly modulating cardiovascular and metabolic phenotypes. We examined the hypothesis that G/R16 and Q/E27 polymorphism of ADRB2, or their haplotypes, may modulate blood pressure, cardiovascular structure, and function or metabolic cardiovascular risk...
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