Article
Dynameomics: a comprehensive database of protein dynamics.
Structure (London, England : 1993) - 14 Mar 2010
van der Kamp Marc W, Schaeffer R Dustin, Jonsson Amanda L, Scouras Alexander D, Simms Andrew M, Toofanny Rudesh D, Benson Noah C, Anderson Peter C, Merkley Eric D, Rysavy Steven, Bromley Dennis, Beck David A C, Daggett Valerie
Abstract excerpt
The dynamic behavior of proteins is important for an understanding of their function and folding. We have performed molecular dynamics simulations of the native state and unfolding pathways of over 2000 protein/peptide systems (approximately 11,000 independent simulations) representing the majority of folds in globular proteins. These data are stored and organized using an innovative database approach, which can...
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