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Article

Molecular Mechanisms Underlying Lymphovascular Invasion in Invasive Breast Cancer

1 Jan 2015

Abstract excerpt

Lymphovascular invasion (LVI), the presence of malignant cells within lymphovascular channels, is a crucial step in the invasion-metastasis cascade. LVI, when identified morphologically in the peritumoural area, is regarded as an indicator of metastatic potential and is strongly associated with a poor prognosis in many solid tumours, including breast cancer (BC). Although molecular mechanisms associated with the...

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PMID: 26330352
DOI: 10.1159/000433583

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