Article
Mutations at BRCA1: the medullary breast carcinoma revisited.
Cancer research - 15 Apr 1998
Eisinger F, Jacquemier J, Charpin C, Stoppa-Lyonnet D, Bressac-de Paillerets B, Peyrat J P, Longy M, Guinebretière J M, Sauvan R, Noguchi T, Birnbaum D, Sobol H
Abstract excerpt
BRCA1-associated breast cancers (BRCA1-BCs) frequently harbor a high histoprognostic grade, p53 alterations, and estrogen receptor negativity. Although these parameters predict a poor outlook, the overall survival in BRCA1-BCs is equivalent to or even better than that in sporadic cases. These fea...
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