Article
Histological features of extratumoral breast lesions as a predictive factor of familial breast cancer.
Oncology reports - 1 Jun 2010
Mangia Anita, Tommasi Stefania, Bruno Michele, Malfettone Andrea, D'Amico Cosimo, Zito Francesco Alfredo, Paradiso Angelo, Simone Giovanni
Abstract excerpt
The aim of this study was to verify whether histopathological features of extratumoral and of primary tumor breast tissue could play a role in identifying patients with familial characteristics. We examined the clinicopathological features of 504 patients with sporadic or familial breast cancer stratified for risk of BRCA mutation. Patients with a higher risk of being carrier of BRCA gene mutations were...
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