Article
JISTIC: identification of significant targets in cancer.
BMC bioinformatics - 14 Apr 2010
Sanchez-Garcia Felix, Akavia Uri David, Mozes Eyal, Pe'er Dana
Abstract excerpt
BACKGROUND: Cancer is caused through a multistep process, in which a succession of genetic changes, each conferring a competitive advantage for growth and proliferation, leads to the progressive conversion of normal human cells into malignant cancer cells. Interrogation of cancer genomes holds the promise of understanding this process, thus revolutionizing cancer research and treatment. As datasets measuring copy...
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