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Article

OncoScape: Exploring the cancer aberration landscape by genomic data fusion.

Scientific reports - 20 Jun 2016

Schlicker Andreas, Michaut Magali, Rahman Rubayte, Wessels Lodewyk F A

Abstract excerpt

Although large-scale efforts for molecular profiling of cancer samples provide multiple data types for many samples, most approaches for finding candidate cancer genes rely on somatic mutations and DNA copy number only. We present a new method, OncoScape, which exploits five complementary data types across 11 cancer types to identify new candidate cancer genes. We find many rarely mutated genes that are strongly...

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PMID: 27321817
DOI: 10.1038/srep28103
PMCID: PMC4913322

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MSRA
STK31

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