Article
Photoinitiated singlet and triplet electron transfer across a redesigned [myoglobin, cytochrome b5] interface.
Journal of the American Chemical Society - 5 May 2010
Nocek Judith M, Knutson Amanda K, Xiong Peng, Co Nadia Petlakh, Hoffman Brian M
Abstract excerpt
We describe a strategy by which reactive binding of a weakly bound, 'dynamically docked (DD)' complex without a known structure can be strengthened electrostatically through optimized placement of surface charges, and discuss its use in modulating complex formation between myoglobin (Mb) and cytochrome b(5) (b(5)). The strategy employs paired Brownian dynamics (BD) simulations, one which monitors overall binding,...
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