Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Charge-Disproportionation Symmetry Breaking Creates a Heterodimeric Myoglobin Complex with Enhanced Affinity and Rapid Intracomplex Electron Transfer.

Journal of the American Chemical Society - 28 Sept 2016

Trana Ethan N, Nocek Judith M, Woude Jon Vander, Span Ingrid, Smith Stephen M, Rosenzweig Amy C, Hoffman Brian M

Abstract excerpt

We report rapid photoinitiated intracomplex electron transfer (ET) within a "charge-disproportionated" myoglobin (Mb) dimer with greatly enhanced affinity. Two mutually supportive Brownian Dynamics (BD) interface redesign strategies, one a new "heme-filtering" approach, were employed to "break the symmetry" of a Mb homodimer by pairing Mb constructs with complementary highly positive and highly negative net...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cytochromes b5
Share to Electrochemistry

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Electron Transport

Share to Models, Molecular

Share to Molecular Dynamics Simulation

Share to Myoglobin

Share to Photochemical Processes

Share to Protein Conformation

Source

Open in PubMed Open full text

Identifiers

PMID: 27646786
DOI: 10.1021/jacs.6b07672
PMCID: PMC5068489

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Charge-Disproportionation Symmetry Breaking Creates a Heterodimeric Myoglobin Complex with Enhanced Affinity and Rapid Intracomplex Electron Transfer.PMID 27646786Read ↗

Photoinitiated singlet and triplet electron transfer across a redesigned [myoglobin, cytochrome b5] interface.Semantic proximity Read ↗

Interfacial hydration, dynamics and electron transfer: multi-scale ET modeling of the transient [myoglobin, cytochrome b5] complex.Semantic proximity Read ↗

Ultra-Fast Bioorthogonal Spin-Labeling and Distance Measurements in Mammalian Cells Using Small, Genetically Encoded Tetrazine Amino AcidsSemantic proximity Read ↗

Structural dynamics of myoglobin: an infrared kinetic study of ligand migration in mutants YQR and YQRF.Semantic proximity Read ↗

Ultrafast measurements of geminate recombination of NO with site-specific mutants of human myoglobin.Semantic proximity Read ↗

Protein ligand migration mapped by nonequilibrium 2D-IR exchange spectroscopy.Semantic proximity Read ↗

An engineered heme-copper center in myoglobin: CO migration and binding.Semantic proximity Read ↗

Engineered bi-histidine metal chelation sites map the structure of the mechanical unfolding transition state of an elastomeric protein domain GB1.Semantic proximity Read ↗

The position 68(E11) side chain in myoglobin regulates ligand capture, bond formation with heme iron, and internal movement into the xenon cavities.Semantic proximity Read ↗

Effects of interface mutations on association modes and electron-transfer rates between proteins.Semantic proximity Read ↗

Metal migration and subunit swapping in ALS-linked SOD1: Zn2+ transfer between mutant and wild-type occurs faster than the rate of heterodimerization.Semantic proximity Read ↗

Structural dynamics of myoglobin: ligand migration among protein cavities studied by Fourier transform infrared/temperature derivative spectroscopy.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.