Ultrafast measurements of geminate recombination of NO with site-specific mutants of human myoglobin.

doi:10.1006/jmbi.1994.1302

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Article

Ultrafast measurements of geminate recombination of NO with site-specific mutants of human myoglobin.

Journal of molecular biology - 6 May 1994

Petrich J W, Lambry J C, Balasubramanian S, Lambright D G, Boxer S G, Martin J L

Abstract excerpt

Flash photolysis studies of NO recombination to heme proteins offer a direct probe of protein structural changes on the tens of picoseconds timescale where they can be compared with molecular dynamics simulations. The geminate recombination of NO to site-specific mutants of human myoglobin (Mb) w...

Topics

Asparagine
Histidine
Humans
Lysine
Mutagenesis, Site-Directed
Mutation
Myoglobin
Nitric Oxide
Photolysis
Structure-Activity Relationship
Thermodynamics
Valine

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