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Article

Lack of association between glutathione S-transferase polymorphisms and primary glioma in a case-control study in Rio de Janeiro.

Genetics and molecular research : GMR - 23 Mar 2010

Coutinho P, Sandim V, Oliveira J A, Alves G, Hatagima A

Abstract excerpt

The glutathione S-transferases (GSTs), a family of phase II isozymes, detoxify several carcinogens. Genetic variations in GSTs have been associated with increased risk for cancer due to a heritable deficiency in detoxification pathways for environmental carcinogens. Conflicting findings have been reported about the association between constitutive GST polymorphisms and gliomas in different populations. The...

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Source

Identifiers

PMID: 20391338
DOI: 10.4238/vol9-1gmr753

Genes

GSTM1
GSTM3
GSTP1
GSTT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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