Article
Glutathione S-transferase polymorphisms and oral cancer: a case-control study in Rio de Janeiro, Brazil.
Oral oncology - 1 Feb 2008
Hatagima Ana, Costa Emmerson C B, Marques Christiane F S, Koifman Rosalina J, Boffetta Paolo, Koifman Sergio
Abstract excerpt
This study evaluates the influence of genetic polymorphisms at GSTM1, GSTT1 and GSTP1 gene loci on oral cancer susceptibility among Brazilians from Rio de Janeiro. DNA extracted from white blood cells of 231 oral cancer patients and 212 hospital controls was analyzed by polymerase chain reaction (PCR) and restriction fragment length polymorphism (RFLP) methods. GSTM1 polymorphism distribution was different...
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