Article
Genetic polymorphisms of GSTs and their association with primary brain tumor incidence.
Cancer genetics and cytogenetics - 15 Jan 2005
Pinarbasi Hatice, Silig Yavuz, Gurelik Mustafa
Abstract excerpt
Glutathione S-transferases GSTM1, GSTT1, and GSTP1 are phase II biotransformation enzymes that function on detoxification of a wide range of exogenous agents including carcinogens. It has been shown that genetic variations in these genes play an important role in determining the response of an individual to environmental carcinogens. Some studies revealed a statistically significant association between the...
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