Article
Selection criteria for c-Met-targeted therapies: emerging evidence for biomarkers.
Biomarkers in medicine - 1 Feb 2010
Goetsch Liliane, Caussanel Véronique
Abstract excerpt
Extensive development of targeted therapies emphasize the critical need for biomarkers and major efforts have been engaged to identify screening, prognostic, stratification and therapy-monitoring markers. One of the challenges in translating preclinical studies into effective clinical therapies remains the accurate identification of a responsive subsets of patients. Studies on trastuzumab demonstrated that...
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