Article
MET in Lung Cancer: Biomarker Selection Based on Scientific Rationale.
Molecular cancer therapeutics - 1 Apr 2017
Salgia Ravi
Abstract excerpt
MET or hepatocyte growth factor (HGF) receptor pathway signaling mediates wound healing and hepatic regeneration, with pivotal roles in embryonic, neuronal, and muscle development. However, dysregulation of MET signaling mediates proliferation, apoptosis, and migration and is implicated in a number of malignancies. In non-small cell lung cancer (NSCLC), aberrant MET signaling can occur through a number of...
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