Article
Biomarker development in MET-targeted therapy.
Oncotarget - 14 Jun 2016
Zhang Yanni, Du Zhiqiang, Zhang Mingqiang
Abstract excerpt
Activation of the MET receptor tyrosine kinase by its ligand, hepatocyte growth factor (HGF), has been implicated in a variety of cellular processes, including cell proliferation, survival, migration, motility and invasion, all of which may be enhanced in human cancers. Aberrantly activated MET/HGF signaling correlates with tumorigenesis and metastasis, and is regarded as a robust target for the development of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
