Article
Association between DNA damage response and repair genes and risk of invasive serous ovarian cancer.
PloS one - 8 Apr 2010
Schildkraut Joellen M, Iversen Edwin S, Wilson Melanie A, Clyde Merlise A, Moorman Patricia G, Palmieri Rachel T, Whitaker Regina, Bentley Rex C, Marks Jeffrey R, Berchuck Andrew
Abstract excerpt
BACKGROUND: We analyzed the association between 53 genes related to DNA repair and p53-mediated damage response and serous ovarian cancer risk using case-control data from the North Carolina Ovarian Cancer Study (NCOCS), a population-based, case-control study. METHODS/PRINCIPAL FINDINGS: The analysis was restricted to 364 invasive serous ovarian cancer cases and 761 controls of white, non-Hispanic race....
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