Article
Association between invasive ovarian cancer susceptibility and 11 best candidate SNPs from breast cancer genome-wide association study.
Human molecular genetics - 15 Jun 2009
Song Honglin, Ramus Susan J, Kjaer Susanne Krüger, DiCioccio Richard A, Chenevix-Trench Georgia, Pearce Celeste Leigh, Hogdall Estrid, Whittemore Alice S, McGuire Valerie, Hogdall Claus, Blaakaer Jan, Wu Anna H, Van Den Berg David J, Stram Daniel O, Menon Usha, Gentry-Maharaj Aleksandra, Jacobs Ian J, Webb Penny M, Beesley Jonathan, Chen Xiaoqing, Rossing Mary Anne, Doherty Jennifer A, Chang-Claude Jenny, Wang-Gohrke Shan, Goodman Marc T, Lurie Galina, Thompson Pamela J, Carney Michael E, Ness Roberta B, Moysich Kirsten, Goode Ellen L, Vierkant Robert A, Cunningham Julie M, Anderson Stephanie, Schildkraut Joellen M, Berchuck Andrew, Iversen Edwin S, Moorman Patricia G, Garcia-Closas Montserrat, Chanock Stephen, Lissowska Jolanta, Brinton Louise, Anton-Culver Hoda, Ziogas Argyrios, Brewster Wendy R, Ponder Bruce A J, Easton Douglas F, Gayther Simon A, Pharoah Paul D P
Abstract excerpt
Because both ovarian and breast cancer are hormone-related and are known to have some predisposition genes in common, we evaluated 11 of the most significant hits (six with confirmed associations with breast cancer) from the breast cancer genome-wide association study for association with invasive ovarian cancer. Eleven SNPs were initially genotyped in 2927 invasive ovarian cancer cases and 4143 controls from six...
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