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Article

Investigation of Polymorphisms in Global Genome Repair Genes in Patients With Ovarian Cancer in the Turkish Population.

Cancer control : journal of the Moffitt Cancer Center - 1 Jan 2000

Barham Sara Yaser, Omotade Dorcas, Yılmaz Seda, Akdeniz Fatma Tuba, Goralı Betül Çapar, Attar Rukset, İsbir Turgay

Abstract excerpt

INTRODUCTION: Ovarian cancer (OC) poses significant challenges due to its high mortality rate, particularly in advanced stages where symptoms may not be evident. DNA repair mechanisms, including nucleotide excision repair (NER), are crucial in maintaining genomic stability and preventing cancer. This study focuses on exploring the role of two NER-related genes, Xeroderma Pigmentosum Complementation Group C (XPC)...

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Aged
Case-Control Studies
DNA-Binding Proteins
DNA Repair
Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Ovarian Neoplasms

Polymorphism, Single Nucleotide

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Identifiers

PMID: 39090825
DOI: 10.1177/10732748241270597
PMCID: PMC11378165

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