Article
Phosphorylation of Not4p functions parallel to BUR2 to regulate resistance to cellular stresses in Saccharomyces cerevisiae.
PloS one - 8 Apr 2010
Lau Nga-Chi, Mulder Klaas W, Brenkman Arjan B, Mohammed Shabaz, van den Broek Niels J F, Heck Albert J R, Timmers H Th Marc
Abstract excerpt
BACKGROUND: The evolutionarily conserved Ccr4-Not and Bur1/2 kinase complexes are functionally related in Saccharomyces cerevisiae. In this study, we further explore the relationship between the subunits Not4p and Bur2p. METHODOLOGY/PRINCIPAL FINDINGS: First, we investigated the presence of post-translational modifications on the Ccr4-Not complex. Using mass spectrometry analyses we identified several SP/TP...
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