Article
Genotype-by-diet interactions drive metabolic phenotype variation in Drosophila melanogaster.
Genetics - 1 Jul 2010
Reed Laura K, Williams Stephanie, Springston Mastafa, Brown Julie, Freeman Kenda, DesRoches Christie E, Sokolowski Marla B, Gibson Greg
Abstract excerpt
The rising prevalence of complex disease suggests that alterations to the human environment are increasing the proportion of individuals who exceed a threshold of liability. This might be due either to a global shift in the population mean of underlying contributing traits, or to increased variance of such underlying endophenotypes (such as body weight). To contrast these quantitative genetic mechanisms with...
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