Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Generation of ES cells for conditional expression of nuclear receptors and coregulators in vivo.

Molecular endocrinology (Baltimore, Md.) - 1 Jun 2010

Wu San-Pin, Lee Dong-Kee, Demayo Francesco J, Tsai Sophia Y, Tsai Ming-Jer

Abstract excerpt

Nuclear receptors and coregulators orchestrate diverse aspects of biological functions and inappropriate expression of these factors often associates with human diseases. The present study describes a conditional overexpression system consisting of a minigene located at the Rosa26 locus in the genome of mouse embryonic stem (ES) cells. Before activation, the minigene is silent due to a floxed STOP cassette...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Cell Line
Share to Embryonic Stem Cells

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Receptors, Cytoplasmic and Nuclear

Share to Uterus

Source

Open in PubMed Open full text

Identifiers

PMID: 20382891
DOI: 10.1210/me.2010-0068
PMCID: PMC2875802

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Generation of ES cells for conditional expression of nuclear receptors and coregulators in vivo.PMID 20382891Read ↗

Deletion of the orphan nuclear receptor COUP-TFII in uterus leads to placental deficiencySemantic proximity Read ↗

Generation of a mouse model for a conditional inactivation of Gtf2i allele.Semantic proximity Read ↗

COUP-TF orphan nuclear receptors in development and differentiationSemantic proximity Read ↗

Molecular mechanism of chicken ovalbumin upstream promoter-transcription factor (COUP-TF) actionsSemantic proximity Read ↗

Dynamic expression of COUP-TFI and COUP-TFII during development and functional maturation of the mouse inner ear.Semantic proximity Read ↗

COUP-TFII Mediates Progesterone Regulation of Uterine Implantation by Controlling ER ActivitySemantic proximity Read ↗

COUP-TFII Regulates Human Endometrial Stromal Genes Involved in InflammationSemantic proximity Read ↗

An ES cell system for rapid, spatial and temporal analysis of gene function in vitro and in vivo.Semantic proximity Read ↗

Chicken ovalbumin upstream promoter transcription factor type II interacts and functionally cooperates with GATA4 to regulate anti‐Müllerian hormone receptor type 2 transcription in mouse MA‐10 Leydig cellsSemantic proximity Read ↗

Generation of heterozygous (MCRIi030-A-1) and homozygous (MCRIi030-A-2) NR2F2/COUP-TFII knockout human iPSC lines.Semantic proximity Read ↗

Generation of a germ cell nuclear factor conditional allele in mice.Semantic proximity Read ↗

Essential Roles of COUP-TFII in Leydig Cell Differentiation and Male FertilitySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.