Article
T-cell receptor gamma: a microsatellite marker for colorectal cancer.
Annals of surgical oncology - 1 Jan 2000
Uthoff Sonja M S, Hunt Louise E, Grant Brooke S, Young Vy Vy, Eichenberger M Robert, Cobbs Gary A, Galandiuk Susan
Abstract excerpt
BACKGROUND: T-cell receptor gamma (TCR-gamma) is involved in maintaining host cell integrity and homeostasis of the human immune system. We hypothesize that polymorphism of the TCR-gamma complex may be involved in the pathogenesis of colorectal cancer. METHODS: The microsatellite markers D7S1818 and D7S2206 located within the TCR-gamma antigen locus on chromosome 7p were amplified by polymerase chain reaction,...
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