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Article

Glucocorticoid receptor gene, low-grade inflammation, and heart failure: the Heart and Soul study.

The Journal of clinical endocrinology and metabolism - 1 Jun 2010

Otte Christian, Wüst Stefan, Zhao Shoujun, Pawlikowska Ludmila, Kwok Pui-Yan, Whooley Mary A

Abstract excerpt

CONTEXT: A common haplotype of the glucocorticoid receptor (GR) gene has been associated with increased susceptibility to coronary heart disease (CHD). Whether this haplotype predisposes to heart failure (HF) is unknown. OBJECTIVE: The objective of the study was to determine whether GR haplotype 3 is associated with HF and whether this association is explained by low-grade inflammation (C-reactive protein)....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 20371666
DOI: 10.1210/jc.2009-2251

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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