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Article

Mutant superoxide dismutase 1 overexpression in NSC-34 cells: effect of trehalose on aggregation, TDP-43 localization and levels of co-expressed glycoproteins.

Neuroscience letters - 21 May 2010

Gomes Catarina, Escrevente Cristina, Costa Júlia

Abstract excerpt

Protein inclusions rich in mutant Cu,Zn superoxide dismutase (SOD1) have been found in tissues from patients with familial amyotrophic lateral sclerosis (ALS). Here, the mouse motor neuron-like NSC-34 cell line transiently transfected with human SOD1(G93A) fused to enhanced green fluorescent protein exhibited aggregates contrary to cells overexpressing wild-type human SOD1. The aggregates were immunoreactive for...

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PMID: 20363292
DOI: 10.1016/j.neulet.2010.03.065

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SOD1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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