Article
Protein aggregation in motor neurone disorders.
Neuropathology and applied neurobiology - 1 Dec 2003
Wood J D, Beaujeux T P, Shaw P J
Abstract excerpt
Toxicity associated with abnormal protein folding and protein aggregation are major hypotheses for neurodegeneration. This article comparatively reviews the experimental and human tissue-based evidence for the involvement of such mechanisms in neuronal death associated with the motor system disor...
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