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Article

Superoxide dismutase 1 mutants related to amyotrophic lateral sclerosis induce endoplasmic stress in neuro2a cells.

Journal of neurochemistry - 1 Feb 2008

Oh Yeo Kyoung, Shin Ki Soon, Yuan Junying, Kang Shin Jung

Abstract excerpt

One of the common features of damaged neurons in many neurodegenerative diseases is the presence of abnormal aggregates of the disease-related proteins. In amyotrophic lateral sclerosis (ALS) of both sporadic and familial forms, protein aggregates are found in the affected spinal cords. In familial ALS with mutations in copper-zinc superoxide dismutase 1 (SOD1), the propensity of SOD1 for aggregation is known to...

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Source

Identifiers

PMID: 18233996
DOI: 10.1111/j.1471-4159.2007.05053.x

Genes

SOD1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Superoxide dismutase 1 mutants related to amyotrophic lateral sclerosis induce endoplasmic stress in neuro2a cells.PMID 18233996Read ↗

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