Article

Novel Findings From Family-based Exome Sequencing for Children With Biliary Atresia

2021-06-02

Abstract excerpt

Biliary atresia (BA) is a progressive inflammation and fibrosis of the biliary tree, characterized by the obstruction of bile flow led to liver failure, scarring and cirrhosis. This study aimed to explore the elusive etiology of BA by conducting whole exome sequencing (WES) for 41 children with BA and their parents (35 trios, including one family with two BA diagnosed children and five child-mother cases). We excl...

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Literature Corpus work: 0851ab9d-f92e-52da-82e1-6fe00301a6ab
DOI: 10.21203/rs.3.rs-561902/v1

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