Article
RNA processing pathways in amyotrophic lateral sclerosis.
Neurogenetics - 1 Jul 2010
van Blitterswijk Marka, Landers John E
Abstract excerpt
RNA processing is a tightly regulated, highly complex pathway which includes RNA transcription, pre-mRNA splicing, editing, transportation, translation, and degradation of RNA. Over the past few years, several RNA processing genes have been shown to be mutated or genetically associated with amyotrophic lateral sclerosis (ALS), including the RNA-binding proteins TDP-43 and FUS/TLS. These findings suggest that RNA...
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